Max-Delbrück-Centrum für Molekulare Medizin in der Helmholtz-Gemeinschaft

Album

Album is open-source infrastructure for building executable digital libraries of reusable, discoverable, and reproducible scientific software methods.

DeBCR

DeBCR is a sparsity-efficient deep learning framework for denoising, deblurring, and deconvolving fluorescence microscopy images. Using the m-rBCR model, it restores structural details and improves resolution. It is available as a Python package and napari plugin for efficient image restoration.

metadeconfoundR

Using non-parametric tests, naive associations between omics features and metadata in cross-sectional data-sets are detected. In a second step, confounding effects between metadata associated to the same omics feature are detected and labeled using nested post-hoc model comparison tests.

methylKit

methylKit is an R package for DNA methylation analysis and annotation from high-throughput bisulfite sequencing. The package is designed to deal with sequencing data from RRBS and its variants, but also target-capture methods and whole genome bisulfite sequencing.

novoSpaRc

novoSpaRc predicts locations of single cells in space by solely using single-cell RNA sequencing data. An existing reference database of marker genes is not required, but significantly enhances performance if available.

O2A SEQUENCES

O2A SEQUENCES provides a single platform for the full metabarcoding lifecycle: it keeps samples, metadata, and sequences linked, runs containerized workflows that produce provenance-tracked ASV tables, generates submission-ready exports for public archives, and delivers AI-ready outputs.

PiGx

PiGx is a collection of genomics pipelines. All pipelines are easily configured with a simple sample sheet and a descriptive settings file. The result is a set of comprehensive, interactive HTML reports with interesting findings about your samples.

Polarityjam

PP

Pixel-Patrol

spacemake

Processing and analysis of large-scale spatial transcriptomics data

TomoBEAR

TomoBEAR is an open-source configurable and customizable modular pipeline for streamlined and parallelized processing of large-scale cryo-electron tomography data for subtomogram averaging.

VarFish

VarFish is a user-friendly web application for the quality control, filtering, prioritization, analysis, and user-based annotation of DNA variant data with a focus on rare disease genetics. It is capable of processing variant call files with single or multiple samples. ...